Organ and blood donation are two distinct but equally vital ways to save lives. Organ donation involves registering your decision to donate organs and tissues after death (or as a living donor), while blood donation is an ongoing process where healthy individuals give blood for transfusions and medical treatments.
38 steps across 9 sections
1. How to Register
- Online via RegisterMe.org — The National Donate Life Registry at registerme.org allows you to sign up in minutes
- At the DMV — When getting or renewing your driver's license or state ID, you can indicate your wish to be a donor (the heart symbol on your license)
- iPhone Health App — Apple's Health app includes organ donor registration
- State Donate Life websites — Each state has its own Donate Life team and registry (e.g., DonateLifePA.org, DonateLifeKY.org)
- OrganDonor.gov — Federal resource with links to your state's registry
2. State vs. National Registries
- The National Donate Life Registry (RegisterMe.org) and your state donor registry are two separate registries for most states
- Both registries are checked by donation professionals at the time of death
- The most recent donor registration is honored as your legal document of gift
- Register in both for maximum coverage
3. Eligibility
- Anyone age 18 or older can register regardless of age or medical history
- In some states, people ages 15-17 can sign up (with parental consent in some cases)
- Medical suitability is determined at the time of death — don't self-disqualify
- People with chronic conditions, past cancers, or older age can still be donors
4. Managing Your Registration
- Visit RegisterMe.org and click "Edit Registration" to access your donor record
- You can update your address, add research as a donation option, and list donation preferences
- Tell your family about your decision — they may be consulted even if you're registered
5. Types of Organ/Tissue Donation
- Deceased donation: Organs (heart, lungs, liver, kidneys, pancreas, intestines), tissues (corneas, skin, bone, heart valves, tendons)
- Living donation: One kidney, part of liver, part of lung, part of intestine, blood, bone marrow/stem cells
6. General Eligibility Requirements
- Age: At least 16-17 years old (varies by state)
- Weight: At least 110 pounds (higher minimums for some donation types)
- Health: Must feel well on the day of donation
- Controlled chronic conditions (diabetes, high blood pressure) are usually fine
- No tattoo waiting period in most states if done at a regulated facility
7. Common Disqualifications
- Recent travel to malaria-endemic areas
- Certain medications (check with donation center)
- Recent illness or infection
- Low iron/hemoglobin (tested at donation)
- Pregnancy or recent childbirth
- Recent surgery or dental work (varies)
8. The Donation Process
- Register — Sign up online or walk in at a blood center or blood drive
- Health history form — Complete questionnaire about medical history, travel, medications
- Mini-physical — Staff checks blood pressure, temperature, pulse, and hemoglobin via finger prick
- Donation — Actual blood draw takes 8-10 minutes for whole blood
- Rest and refreshments — Spend 10-15 minutes in the canteen area with snacks and drinks
- Total time — About 1 hour for the entire process
9. Power Red Requirements
- More restrictive than whole blood
- Men: at least 17 years old, 5'1" tall, 130+ pounds
- Women: at least 19 years old, 5'3" tall, 150+ pounds
Common Mistakes
- Not telling your family
- Assuming you're registered
- Not registering in both
- Self-disqualifying
- Donating blood on an empty stomach
Pro Tips
- Register online AND at the DMV
- Tell at least 3 family members
- Include donation wishes
- Consider living donation
- Register for bone marrow
Sources
- RegisterMe.org - National Donate Life Registry
- OrganDonor.gov - Sign Up
- OrganDonor.gov - How to Sign Up
- Donate Life America
- Donate Life America - National Registry
- Red Cross - Blood Donation Eligibility
- Vitalant - Blood Donation Requirements
- Vitalant - Donation Age, Weight, Frequency Limits
- University of Iowa - Blood Donation Eligibility, Process, and Intervals